My research focuses on functional genomics to understand the function of human genes on large scale. I conduct whole-genome CRISPR-inhibition screens in human induced pluripotent cells (hIPSC) and hIPSC derived cells to identify genes important for cell survival, growth, or other phenotypes.
Besides healthy background, my screens in disease mutation background aim to identify conditional lethal genes, which will ultimately illuminate disease mechanisms.
With combinatorial screens targeting multiple genes at once, I aim to understand gene to gene interactions in hiPSC and hiPSC derived cells.
My timeline
Joined Wellcome Sanger Institute as Janet Thornton Postdoctoral Fellow
Career break
Continued my work at Hande Caglayan lab as a postdoctoral scientist on Benign familial epilepsy syndromes
PhD in Human Genetics from Bogazici University, Department of Molecular Biology and Genetics, Istanbul, Turkey
Started working as a research and teaching assistant at Bogazici University, Department of Molecular Biology and Genetics, Istanbul, Turkey
MSc in Human Genetics from Bogazici University, Department of Molecular Biology and Genetics, Istanbul, Turkey
Visiting Scientist at TUBITAK, Genetic Engineering, and Biotechnology Institute, Kocaeli, Turkey
BSc at Bogazici University, Department of Molecular Biology and Genetics, Istanbul, Turkey
Summer internship at Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany