Kenny's research focuses upon developing and applying wide-scale spatial transcriptomics approaches to analyse human cell diversity.

My research combines state-of-the-art single molecule in situ hybridisation and sequencing technologies with cutting edge high-throughput microscopy to visualise the expression of genes within human tissues in a spatially resolved manner.

Kenny Roberts, Bayraktar lab, Wellcome Sanger Institute.
Cortical layers in mouse brain. Kenny Roberts, Wellcome Sanger Institute.

The world of spatial genomics and transcriptomics has exploded in recent years, along with the breadth of technologies available. I work closely between external collaborators and commercial partners, and Sanger faculty teams and pipelines in order to develop, transfer, and establish spatial technologies such as Xenium in situ sequencing as resources for the institute. I collaborate with colleagues in histology, microscopy, and image analysis to generate spatially-resolved biological data that complement single-cell transcriptomic approaches.

I am particularly interested in the application of these cutting-edge technologies to biological models and questions. I have previously collaborated with faculty teams in Cellular Genetics and CASM to generate multi-modal atlases of human tissues, including the uterus and placenta (Vento-Tormo), gastrointestinal tract and heart (Teichmann), spine (Behjati), and breast (Yates).

My timeline

 

My publications

Loading publications...