Sepsis Study Explanation diagram

The study is designed to collect blood samples from patients with sepsis and analyse the gene expression levels of seven key genes.

Based on the results of this analysis, the patients are placed into one of two categories:

SRS1 (Subgroup 1) – these patients have:

• A more severe immune response.
• Immune cell exhaustion.
• Dysregulated cell metabolism.

SRS1 (Subgroup 2) – these patients have:

• A less severe immune response.
• Immune cell activation.
• Regular cell metabolism.

Further research, including clinical trials, is being carried out on both subgroups of patients to develop personalised treatment options.

It is hoped that this work will, in the future, lead to targeted treatments that are personalised by subgroup.

Back to the News story – Sepsis patients could get the right treatment faster, based on their genes