Molecular Cytogenetics
Scientific Operations
Archive Page
This page is maintained as a historical record and is no longer being updated.
![](/wp-content/uploads/screen_shot_2015-10-15_at_12.26.10.png)
Nearly all our services rely on FISH, including physical mapping by metaphase-, interphase- and fibre-FISH; karyotyping of cancer and reprogrammed cell lines by Multiplex-FISH, studying the evolutionary chromosome rearrangement by cross-species chromosome painting etc.
Currently we can provide the following FISH services:
1. Physical assigment of BACs, fosmids, transgenes, cDNA clones onto metaphase chromosomes.
2. High-resolution mapping and gap sizing by fibre-FISH with single-molecule DNA fibres and extended chromomatin fibres.
3. Karyotyping by combined M-FISH and inverted DAPI-banding.
4. Validation of structural and copy number variations.
5. Multi-directional chromosome painting
Please submit your requests via: fish-requests@sanger.ac.uk
Previous team members
![Ms Beiyuan Fu Photo of Ms Beiyuan Fu](/userpics/200/bf2.jpg)
Ms Beiyuan Fu
Senior Research Assistant
![Sandra Louzada Gomes Pereira Photo of Sandra Louzada Gomes Pereira](/userpics/200/sg14.jpg)
Sandra Louzada Gomes Pereira
Senior Research Assistant