Dr Patrick Musicha

International Fellow at the Sanger Institute and Research Fellow at the Liverpool School of Tropical Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Programme in Blantyre, Malawi.

Patrick Musicha is a mathematician, bioinformatician and emerging leader in the field of pathogen genomics. His research focuses on understanding the evolution and spread of AMR, particularly in ESBL producing Enterobacteriaceae. He combines whole-genome sequencing and epidemiological and data to model the carriage and transmission dynamics of ESBL-producing Enterobacteriaceae, both in Southeast Asia and Europe.

Collaborative Projects

Patrick is the project lead for the Wellcome Trust-funded CAPSULE project, which seeks to identify causal pathways to colonisation with extended spectrum beta-lactamase producing Enterobacteriaceae during hospitalisation in a low-income setting. This project utilises mathematical modelling and bioinformatics approaches to analyse bacterial genome data from in-patients and their family carers to investigate the pathways through which ESBL-producing bacteria are carried into and transmitted in a low-income hospital environment, quantifying the roles of antibiotic use, hospital environmental contamination and patient-carer contacts in the hospital dynamics of ESBL-producing bacteria.

Personal Bio

Patrick graduated with a Bsc (Hons) in Mathematics and Statistics from the University of Malawi Chancellor College in 2007, before completing an MSc in Mathematics-Coding Theory and Cryptography at Mzuzu University in 2010.

In 2017, Patrick was awarded his PhD from the University of Liverpool, where he investigated the epidemiology and genomics of AMR in Malawi. His PhD work was undertaken at Malawi-Liverpool-Wellcome Trust Clinical Research Programme (Malawi), the Liverpool School of Tropical Medicine (LSTM), and the Wellcome Sanger Institute (UK).

Following his PhD, Patrick spent four years as a postdoctoral research fellow, first at the Centre for Tropical Medicine and Global Health, University of Oxford, based at the Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand, and then at the Wellcome Sanger Institute.

In 2024, Patrick was selected for the LSTM Career Track Fellowship programme, recognising his excellence in research and teaching.

 

My publications

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