Mouse Phenotyping
Mouse Pipelines
Archive Page
This page is maintained as a historical record and is no longer being updated.
Characterisation was completed for over 1000 mutant mouse lines, with an additional 160 strains processed annually. All the data was made freely available to the scientific community.
We found many unexpected phenotypes, which were detected only because we screened for them, emphasizing the value of screening all mutants for a wide range of traits. The pipeline of knockout mouse generation and phenotyping was world-leading in its effectiveness, sophistication and throughput.
Our mouse strains and data continue to be used by scientists throughout the world, reducing the amount of unnecessary experimental duplication and ensuring a ‘gold standard’ of models for research groups to study.
Related groups
Partners
We worked with the following groups
External
Deciphering the Mechanisms of Developmental Disorders
We focus on characterisation of genes and phenotypes of interest to support the work of this Wellcome Trust-funded Strategic Award
External
Infection and Immunity Immunophenotyping
We focus on characterisation of genes and phenotypes of interest to support the work of this Wellcome Trust-funded Strategic Award
External
Origins of Bone and Cartilage Disease
We focus on characterisation of genes and phenotypes of interest to support the work of this Wellcome Trust-funded Strategic Award
External
International Mouse Phenotyping Consortium
We are a contributing partner in the Consortium, which aims to discover the function of all of the genes in the mouse genome that code for proteins by the use of a broad-spectrum standardised phenotyping platform and data set