Dr Hanna Najgebauer
Alumni
This person is a member of Sanger Institute Alumni.
Hanna worked on integrative computational methods for the identification of new oncology therapeutic targets and biomarkers, maximizing their translational potential via combined analyses of large-scale drug/functional-genomics screening data and genomic profiles of cancer patients.
Within Open Targets, Hanna was responsible for the development of new algorithms and computational tools for optimising the genomic characterization of large panels of cancer in vitro models. This involved the design of scoring methods and assessment routines for evaluating the relevance of immortalised cancer cell lines with respect to matched primary diseases. The aim of her work was to enable researchers to make appropriate informed choices about model inclusion/exclusion in retrospective and future studies, and to identify cancer subtypes currently lacking representative in vitro models.
My publications
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